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Technical notes from the bench

Practical decisions, trade-offs and failure modes in nanobody discovery, protein production and assay development.

First articles in preparation

Coming soon

What animal-free nanobody discovery actually changes

Where synthetic repertoires help, where they do not, and what it means for a discovery campaign.

A practical order of operations for low-yield expression

The checks worth running before redesigning the construct.

Choosing a purification strategy you will not regret

Matching affinity, ion-exchange and size-exclusion steps to the properties of your target.

Have a difficult research problem?

Whether you want to explore the NanoForge platform or need bespoke experimental support, talk to our scientific team.